Could a mitochondrial metabolite known as acetyl L carnitine (LAC) yield a new biomarker for depression and potential new therapies? Dr. Carla Nasca, an @nyugrossman assistant professor of psychiatry and of neuroscience and physiology, Frontiers Carnitine and Depression Effects of Long term Acetyl L carnitine Administration in Rats: I. Increased Dopamine Output in Mesocorticolimbic Areas and Protection toward Acute Stress Exposure Neuropsychopharmacology The Rockefeller University Lack of a single molecule may indicate severe and treatment resistant depression Preventive Role of L Carnitine and Balanced Diet in Alzheimer's Disease Acetyl L Carnitine Mark Hyman, MD